Table 1 PolyP-driven thrombin generation of polyP control
From: Polyphosphate-loaded silk fibroin membrane as hemostatic agent in oral surgery: a pilot study
0.15 | 0.5 | 1.5 | 5 | 15 | 50 | 150 | 500 | |
|---|---|---|---|---|---|---|---|---|
µg/ml polyP | ||||||||
ETP (nM⋅min) | 980.6 ± 201 | 1108.9 ± 75 | 1246.8 ± 79 | 1398.5 ± 76 | 1398.9 ± 44 | 1453.9 ± 23 | 1544.3 ± 55 | 1522.4 ± 3.1 |
Peak thrombin (nM) | 107 ± 31 | 143 ± 14 | 236.6 ± 48 | 316.4 ± 17 | 351.7 ± 11 | 367.6 ± 10 | 382.9 ± 18 | 374.6 ± 5.3 |
Time to peak (min) | 21.7 ± 2.3 | 22.5 ± 0.5 | 19.5 ± 1.2 | 13.2 ± 1.5 | 11 ± 1 | 9.7 ± 0 | 8 ± 0.3 | 7.2 ± 0.2 |
Lag time (min) | 17 ± 2 | 18.7 ± 0.7 | 16.7 ± 1.7 | 11 ± 1.3 | 9.2 ± 1.2 | 8 ± 0 | 6.3 ± 0.3 | 5.5 ± 0.2 |