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Table 1 Overview of characteristics of the included studies (n = 9)

From: Bone envelope for implant placement after alveolar ridge preservation: a systematic review and meta-analysis

Author and year

Design

No. of patients

Treatment-arms (no. of implants)

Healing period/follow-up

Aimetti et al. 2018

[21]

RCT

30

i.DBBM + collagen and membrane (n = 15)

ii.Spont. healing (n = 15)

12 months

Ben Amara et al. 2021

[23]

RCT

34

i.DBBM + collagen and membrane (n = 18)

ii.Spont. healing (n = 16)

6 months

Iorio-Siciliano et al. 2017

[22]

RCT

20

i.DBBM and membrane (n = 10)

ii.Spont. healing (n = 10)

6 months

Iorio-Siciliano et al. 2020

[16]

RCT

40

i.DBBM + collagen and membrane (n = 12)

ii.DBBM and membrane (n = 13)

iii.Spont. healing (n = 15)

6 months

Jonker et al. 2021

[18]

RCT

75

i.DBBM + collagen and collagen matrix (n = 25)

ii.DBBM + collagen and CTG (n = 25)

iii.Spont. healing (n = 25)

2 months

Jung et al. 2013

[17]

RCT

40

i.DBBM + collagen and membrane (n = 10)

ii.Beta-TCP (n = 10)

iii.DBBM + collagen and CTG (n = 10)

iv.Spont. healing (n = 10)

6 months

Jung et al. 2018

[15]

RCT split-mouth

18

i.DBBM and membrane (n = 18)

ii.Spont. healing (n = 18)

3 and 6 months

Machtei et al. 2019

[19]

RCT

33

i.DBBM (n = 11)

ii.Alloplast (n = 11)

iii.Spont. healing (n = 11)

4 months

Stumbras et al. 2021

[20]

RCT

40

i.DBBM and membrane (n = 10)

ii.Allograft and membrane (n = 10)

iii.PRGF (n = 10)

iv.Spont. healing (n = 10)

3 months

  1. DBBM, deproteinized bovine bone mineral; CTG, connective tissue graft; Beta-TCP, beta tricalcium phosphate, PRGF, platelet rich growth factors