From: Horizontal augmentation techniques in the mandible: a systematic review
Author | Year | Study design | Setting | Type of augmentation | Regenerative objective | Interventions | Test/control, n | Preparation | Outcomes measures | ||
---|---|---|---|---|---|---|---|---|---|---|---|
Test | Control | Patients | Sites | ||||||||
Amorfini et al. [101] | 2014 | RCT, parallel, allocation ratio of 1:1, split-mouth model | Private practice | Lateral | Accompanying implant placement | Corticocancellous allograft (iliac crest) + collagen membrane (Biogide®, Geistlich AG) + rhPDGF-BB (GEM 21S®, Osteohealth) or saline solution | Autologous bone chips + bovine bone xenograft (BioOss®, Geistlich) + collagen membrane (Bio-Gide®, Geistlich) + rhPDGF-BB (GEM 21S® Osteohealth) or saline solution | 8/8 | 8/8 | Block graft (treatment) and particulate material (control) | BV, RA, BLCT, BOP, PPD, PI, mBL |
Barbu et al. [100] | 2016 | RCT | University clinic | Lateral | Two-staged | Autogenous ramus block (retromolar) + Autogenous particulate bone + PRF membrane (Group 1) | Autogenous ramus block (retromolar) + Autogenous particulate bone chips mixed with xenograft particulate bone + Pericardium membrane (Group 2) | 12/12 | 12/12 | Crestal incision, block graft, cortical perforation of recipient bed | RA, IS, BG, EX, PGF, TGF |
Beitlitum et al. [117] | 2018 | Retrospective study | Two periodontal practices, one university dental clinic | Lateral | Two-staged | Particulate mineralized bone allograft (MinerOss, BioHorizons or Maxgraft, Botiss) covered with a cross-linked resorbable collagen barrier membrane | – | 15/– | 16/– | Crestal incision, particulate allograft | RA, EX, IS, ME, PGF, TGF |
Di Stefano et al. [104] | 2009 | Case series | Private practice | Lateral | Two-staged | Onlay graft of equine spongy bone layer (Osteoplant Flex, Bioteck, Italy) + titanium-reinforced membrane | – | 5/5 | 5/5 | Onlay xenograft | HA, PGF, TGF, RA |
Nissan et al. [103] | 2011 | RCT | – | Lateral and vertical | Two-staged | Cancellous allograft + mineralized freeze-dried bone allograft (OraGraft, Lifenet), or bovine bone xenograft (BioOss®, Geistlich) + Membranes: Ossix Plus, OraPharma; Ossix, Biomet; Bio-Gide, Geistlich; | Pre-augmentation measurements of crest width and height | 21/– | 29/– | Crestal incision, block graft | WG, WR, ME, HR |
Schwartz-Arad et al. [99] | 2016 | Retrospective study | Outpatient surgical center | Lateral and vertical | Two-staged | Autologous intraoral graft + bovine bone xenograft (BioOss®, Geistlich AG) + platelet-rich plasma (PRP) or platelet-poor plasma (PPP) | – | n/a | 115/– | Crestal incision, block graft | RA, EX, EXH, EXW, Inf, IS, ISC, ME, PGF, TGF, SP |
Silva et al. [105] | 2017 | Prospective study | University clinic | Lateral and vertical | Two-staged | Fresh-frozen bone-block allograft (femoral epiphyses) from tissue bank (UNIOSS, Brazil) + BBM granules (BioOss, Geistlich, Switzerland) + resorbable collagen membrane (Bio-Gide, Geistlich, Switzerland) | – | 20/– | 50/– | block allograft, particulate material | RA, EX, PGF, TGF, BV, HA, IS, mBL, SP, WG |
Urban et al. [102] | 2013 | Case series | University Clinic | Lateral | Two-staged | xenograft (inorganic bovine bone-derived mineral, Bio-Oss) + autologous bone graft + resorbable collagen membrane | – | 13/– | 16/– | particulate material | BV, IS, ISC, PGF, SP, WG, WR |