Overview concerning the main results of clinical studies. ESRD: End-stage renal failure, EDIF: Early dental implant failure. Including orthopantomogram pictures published by Fretwurst et al. 2016 (https://link.springer.com/content/pdf/10.1186/s40729-016-0056-0.pdf), no changes have been made to the figure. Copyright© Tobias Fretwurst, Sebastian Grunert, Johan P. Woelber, Katja Nelson and Wiebke Semper-Hogg (http://creativecommons.org/licenses/by/4.0/).