|  |  |  |  |  | Comparison with Baseline* | ||
---|---|---|---|---|---|---|---|---|
Period | n | Mean | Sd | Median | Min–Max | Difference | 95% CI | p value |
Baseline | 200 | 2.6 | 0.6 | 3.0 | 0.0–4.0 | – |  |  |
 ≤ 1 Y | 146 | 2.5 | 0.6 | 2.5 | 0.0–4.0 | − 0.02 | − 0.11–0.07 | 0.654 |
 ≤2 Y | 112 | 2.6 | 0.6 | 3.0 | 0.0–4.0 | 0.05 | − 0.05–0.15 | 0.343 |
 ≤3 Y | 124 | 2.5 | 0.6 | 2.0 | 0.0–4.0 | 0.04 | − 0.05–0.14 | 0.401 |
 ≤4 Y | 70 | 2.7 | 0.7 | 3.0 | 2.0–5.0 | 0.04 | − 0.07–0.16 | 0.454 |
 ≤5 Y | 118 | 2.5 | 0.7 | 2.0 | 0.0–4.0 | − 0.06 | − 0.16–0.04 | 0.224 |
 ≤6 Y | 38 | 2.8 | 0.7 | 3.0 | 2.0–4.0 | 0.04 | − 0.11–0.19 | 0.628 |
 ≤7 Y | 70 | 2.4 | 0.6 | 2.0 | 2.0–4.0 | − 0.06 | − 0.18–0.05 | 0.277 |
 ≤8 Y | 42 | 2.5 | 0.6 | 2.0 | 1.0–4.0 | − 0.09 | − 0.24–0.05 | 0.209 |
 ≤9 Y | 52 | 2.6 | 0.6 | 2.0 | 2.0–4.0 | 0.12 | − 0.01–0.25 | 0.074 |
 ≤10 Y | 50 | 2.4 | 0.6 | 2.0 | 2.0–4.0 | − 0.03 | − 0.16–0.11 | 0.688 |