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Table 6 Pain assessment outcomes in the evaluated studies

From: Efficacy of platelet-rich fibrin in promoting the healing of extraction sockets: a systematic review

Study n Test Control Results test Results control Statistics
Mourao et al. [56] 32 L-PRF Spontaneous healing 7 days: 4 ± 1.15 7 days: 5.12 ± 1.08 Yes (p = 0.0128)
Ustaoglu et al. [42] 57 L-PRF Spontaneous healing Day 1: 3.30 ± 2.07
Day 2: 0.48 ± 0.92
Day 1:5.11 ± 1.60
Day 2
Day 1: yes (P = 0.047)
Day 2: No
   T-PRF Spontaneous healing Day 1: 3.29 ± 1.85
Day 2: 0.47 ± 0.62
  Day 1: yes (P = 0.047)
Day 2: No
       T-PRF vs. L-PRF
No
Kumar et al. [43] 48 PRF Spontaneous healing Day 1: 0% of the patients Day: 1 18.1% of the patients Not reported
Asmael et al. [58] 20 PRF Spontaneous healing 48 h After Extraction: 0.65 48 h After Extraction: 1.8 No
Temmerman et al. [50] 22 L-PRF Spontaneous healing Day 3: 2,81 Day 3: 3,52 Yes
P = 0.03
Marenzi et al. [57] 26 L-PRF Spontaneous healing 3.2 ± 0.3 4.5 ± 0.7 Yes
P < 0.0001
Yewale et al. [51] 20 Sybograf plus (70% HA and 30% βTCP) mixed with A-PRF + , covered by a Collagen sponge (Collasponge ™) Sybograf plus (70% HA and 30% βTCP), covered by a Collagen sponge (Collasponge ™) Pain frequency after 10 days:
Mild:2
Moderate:8
Pain frequency after 10 days:
Mild:3
Moderate: 7
No