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Table 3 Descriptive characteristics of RCTs

From: Esthetic, mechanical, and biological outcomes of various implant abutments for single-tooth replacement in the anterior region: a systematic review of the literature

Study

No_ patients (baseline)

No_ abutments follow-up (baseline)

Abutment location

Follow-up (years)

Intervention and control abutment type

Andersson et al. 2001 [15]

75

85 (89)

Maxilla and mandible

1-3

Prefabricated alumina/prefabricated Ti

Jung et al. 2008 [13]

30

30

N/A

N/A

Customized Alumina based/customized Ti or gold

Bressan et al. 2011 [22]

20

20

Maxilla

N/A

Customized Ti, gold alloy and Zr/contralateral tooth

Galluci et al. 2011a [51]

Galluci et al. 2011b [52]

20

17 (20)

Maxilla

2

Prefabricated Ti with In-Ceram alumina blank/prefabricated Ti with PFM (cast-on gold coping)

Hosseini et al. 2011 [66]

36

75

Maxilla and mandible

1

Prefabricated Zr/prefabricated metallic

Büchi et al. 2014, Thoma et al. 2016a, Brandenberg et al. 2017 [23, 47, 48]

20

20

Maxilla and mandible

1

Customized Zr with pink ceramic submucosal veneering/customized Zr without veneering

Carrillo de Albornoz et al. 2014 [67]

30

25 (30)

Maxilla

1

Prefabricated Zr/prefabricated Ti

Patil et al. 2014, Patil et al. 2016, Patil et al. 2017 [60,61,62]

26

52

Maxilla and mandible

1

Prefabricated curved grooved Ti/

Prefabricated conventional divergent Ti

Baldini et al. 2016 [68]

24

22 (24)

Maxilla and mandible

1

Prefabricated Zr/prefabricated Ti

Paolantoni et al. 2016 [69]

65

74

Maxilla

4

Customized Zr (1 piece)/customized Zr (2 pieces)

Thoma et al. 2016b [55], Thoma et al. 2018b [56]

44

43 (44)

Maxilla and mandible

1

Customized Zr (screwed)/customized Zr (cemented) with or without submucosal veneering

Gil et al. 2017, Gil et al. 2019, Bittner et al. 2020 [63,64,65]

40

33 (40)

Maxilla

6 months

Customized, pink-anodized Ti/customized gray Ti

Lops et al. 2017 [70]

15

15

Maxilla and mandible

N/A

Customized Ti, gold alloy and Zr/contralateral tooth

Martinez-Rus et al. 2017 [71]

20

20

Maxilla

N/A

Customized Ti, gold-anodized Ti, pink hued Ti, and Zr on Ti-base/contralateral tooth

Thoma et al. 2017 [72]

24

24

Maxilla and mandible

N/A

Customized fluorescent Zr on Ti-base/customized Zr

Wittneben et al. 2017 [58], Wittneben et al. 2020 [59]

40

39 (40)

Maxilla

3

Prefabricated Zr/CAD/CAM Zr

Amorfini et al. 2018 [73]

32

30 (32)

Maxilla

10

Customized Zr with ceramic veneer fused on abutment/customized Zr

Eisner et al. 2018 [49]

20

18 (20)

Maxilla and mandible

3

Customized Zr with pink ceramic submucosal veneering/customized Zr without veneering

Thoma et al. 2018a [54]

33

33

Maxilla and mandible

6 months

Customized Zr directly veneered with veneering ceramic/customized Zr

Heierle et al. 2019 [53]

27

27

Maxilla and mandible

3

Customized Zr directly veneered with veneering ceramic/customized Zr

Laass et al. 2019 [50]

20

16 (20)

Maxilla and mandible

5

Customized Zr with pink ceramic submucosal veneering/customized Zr

Kraus et al. 2019 [57]

44

32 (44)

Maxilla and mandible

3

Customized Zr (screwed)/customized Zr (cemented) with or without submucosal veneering

Koutouzis et al. 2019 [74]

28

26 (27)

Maxilla

1

Customized Ti convex/customized Ti concave profile