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International Journal of Implant Dentistry
Fig. 3 | International Journal of Implant Dentistry

Fig. 3

From: The extract of concentrated growth factor enhances osteogenic activity of osteoblast through PI3K/AKT pathway and promotes bone regeneration in vivo

Fig. 3

Role of PI3K/AKT signaling pathway. a Relative protein expression of MC3T3-E1 cells. Results showed that the protein expression of CGF-e group was significantly higher than the control group. b Relative gene expression level of BMP-2 and OCN after the PI3K/AKT was blocked with the PI3K inhibitor LY294002. Results showed that the gene expression of CGF-e+LY294002 group was significantly lower than the CGF-e group. *p < 0.05; **p < 0.01

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