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Table 1 Descriptive analysis of morphometric parameters for the untreated bone defects and deproteinized bovine bone mineral with collagen (DBBM-C) and lyophilized bovine medullary bone (LBMB) for different post-operative periods

From: Morphometric evaluation of bone regeneration in segmental mandibular bone defects filled with bovine bone xenografts in a split-mouth rabbit model

Morphometric parameters   Baseline line (T0) 3 months (T1) 6 months (T2)
  Unit DBBM-C LBMB Untreated DBBM-C LBMB Untreated DBBM-C LBMB
Bone mineral density mg HA/cm3 310.56 (44.52)c 286.24 (74.6) 442.55 (81.52) 362.88 (93.81) 368.62 (57.58) 419.82 (71.51) 442.1 (63.66)c 363.97 (5.05)
Bone volume fraction (%) 53.86 (7.57)a 31.2 (6.68)a 22.47 (7.15)b 57.18 (16.57)b,a 38.94 (7.87)b,a 22.54 (6.52) 47.20 (25.64) 33.09 (12.46)
Bone surface density (mm2/mm3) 6.55 (0.66)a,c 4.69 (1.02)a,c 1.72 (0.50)b 5.20 (0.85)b 4.25 (0.80)b 1.64 (0.29)b 3.76 (1.34)b,c 3.24 (0.64)b,c
Trabecular thickness (mm) 0.27 (0.02) 0.22 (0.03) 0.47 (0.06) 0.37 (0.10) 0.37 (0.12) 0.58 (0.15) 0.44 (0.15) 0.38 (0.09)
Trabecular number (1/mm) 1.19 (0.24)a,c 1.41 (0.26)a,c 0.47 (0.13)b 1.52 (0.19)b,a 1.10 (0.31)b,a 0.38 (0.04)b 1.04 (0.49)b,c 0.84 (0.19)c
Trabecular separation (mm) 0.30 (0.10)a 0.51 (0.12)a 1.55 (0.47)b 0.35 (0.11)b,a 0.54 (0.15)b,a 1.31 (0.33)b 0.68 (0.48)b 0.80 (0.26)
Trabecular pattern factor (1/mm) − 5.76 (2.56)a 0.81 (1.14)a 0.42 (3.63)b − 5.61 (4.86)b 0.4 (1.73) 2.61 (3.05) − 3.52 (6.28) 1 (2.64)
Structural model index   − 0.38 (0.75)a 0.95 (0.27)a 0.57 (1.95) − 1.39 (3.74) 1.09 (0.56) 1.80 (1.33) − 0.54 (2.70) 1.25 (0.83)
Total porosity (%) 46.13 (7.57)a 68.79 (6.68)a 77.52 (7.15)b 42.81 (16.57)b,a 61.05 (7.87)a 77.45 (6.52) 52.79 (25.64) 66.9 (12.46)
Connective density (1/mm3) 20.62 (4.52)a,c 9.65 (6.58)a 1.63 (0.88)b 13.04 (6.14)b 6.94 (3.08) 1.24 (0.60)b 6.78 (4.32)b,c 3.87 (1.26)
  1. aPost-hoc showed significant statistical difference at the same time point between the grafts (LBMB and DBBM-C)
  2. bPost-hoc showed significant statistical difference at the same time point between the untreated group and the grafts (LBMB or DBBM-C)
  3. cPost-hoc showed significant statistical difference within the same graft experimental group (LBMB or DBBM-C) in different follow up times