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Table 1 Descriptive analysis of morphometric parameters for the untreated bone defects and deproteinized bovine bone mineral with collagen (DBBM-C) and lyophilized bovine medullary bone (LBMB) for different post-operative periods

From: Morphometric evaluation of bone regeneration in segmental mandibular bone defects filled with bovine bone xenografts in a split-mouth rabbit model

Morphometric parameters

 

Baseline line (T0)

3 months (T1)

6 months (T2)

 

Unit

DBBM-C

LBMB

Untreated

DBBM-C

LBMB

Untreated

DBBM-C

LBMB

Bone mineral density

mg HA/cm3

310.56 (44.52)c

286.24 (74.6)

442.55 (81.52)

362.88 (93.81)

368.62 (57.58)

419.82 (71.51)

442.1 (63.66)c

363.97 (5.05)

Bone volume fraction

(%)

53.86 (7.57)a

31.2 (6.68)a

22.47 (7.15)b

57.18 (16.57)b,a

38.94 (7.87)b,a

22.54 (6.52)

47.20 (25.64)

33.09 (12.46)

Bone surface density

(mm2/mm3)

6.55 (0.66)a,c

4.69 (1.02)a,c

1.72 (0.50)b

5.20 (0.85)b

4.25 (0.80)b

1.64 (0.29)b

3.76 (1.34)b,c

3.24 (0.64)b,c

Trabecular thickness

(mm)

0.27 (0.02)

0.22 (0.03)

0.47 (0.06)

0.37 (0.10)

0.37 (0.12)

0.58 (0.15)

0.44 (0.15)

0.38 (0.09)

Trabecular number

(1/mm)

1.19 (0.24)a,c

1.41 (0.26)a,c

0.47 (0.13)b

1.52 (0.19)b,a

1.10 (0.31)b,a

0.38 (0.04)b

1.04 (0.49)b,c

0.84 (0.19)c

Trabecular separation

(mm)

0.30 (0.10)a

0.51 (0.12)a

1.55 (0.47)b

0.35 (0.11)b,a

0.54 (0.15)b,a

1.31 (0.33)b

0.68 (0.48)b

0.80 (0.26)

Trabecular pattern factor

(1/mm)

− 5.76 (2.56)a

0.81 (1.14)a

0.42 (3.63)b

− 5.61 (4.86)b

0.4 (1.73)

2.61 (3.05)

− 3.52 (6.28)

1 (2.64)

Structural model index

 

− 0.38 (0.75)a

0.95 (0.27)a

0.57 (1.95)

− 1.39 (3.74)

1.09 (0.56)

1.80 (1.33)

− 0.54 (2.70)

1.25 (0.83)

Total porosity

(%)

46.13 (7.57)a

68.79 (6.68)a

77.52 (7.15)b

42.81 (16.57)b,a

61.05 (7.87)a

77.45 (6.52)

52.79 (25.64)

66.9 (12.46)

Connective density

(1/mm3)

20.62 (4.52)a,c

9.65 (6.58)a

1.63 (0.88)b

13.04 (6.14)b

6.94 (3.08)

1.24 (0.60)b

6.78 (4.32)b,c

3.87 (1.26)

  1. aPost-hoc showed significant statistical difference at the same time point between the grafts (LBMB and DBBM-C)
  2. bPost-hoc showed significant statistical difference at the same time point between the untreated group and the grafts (LBMB or DBBM-C)
  3. cPost-hoc showed significant statistical difference within the same graft experimental group (LBMB or DBBM-C) in different follow up times