Skip to main content

Table 3 Characteristics of the included studies

From: The impact of simvastatin intervention on the healing of bone, soft tissue, and TMJ cartilage in dentistry: a systematic review and meta-analysis

Included studies

Clear inclusion and exclusion criteria

Randomization method

Assessment parameters (two or more)/validated measurements

Duration of study

With/without carrier and route

Risk of bias

Vaziri et al. 2007

No

2

4 weeks

No carrier/injection

Low

Killeen et al. 2012

No

1

48 days

Systemic/local injection

Low

Kilic et al. 2008

No

2

14 days

Systemic/local

Low

Rutledge et al. 2011

No

1

60 days

Local injections

Low

Ozec et al. 2007

No

2

14 days

Systemic

Low

Sherif et al. 2016

No

1

4 weeks

Topical

Low

Wu Z et al. 2008

No

2

12 weeks

Local

Low

Anbinder et al. 2007

Yes

1

35 days

Oral

Low

George MD et al. 2013

No

1

30 days

Injections/carrier

Low

Holwegner et al. 2015

No

2

28 days

Injections/carrier

Low

Gouda et al. 2017

No

2

9 months

Local

Low

Ranjan et al. 2017

No

2

9 months

Local

Low

Kinra et al. 2010

No

2

24 weeks

Local

Low

Chauhan et al. 2015

No

2

3 months

Local

Low

Pradeep et al. 2012

No

2

6 months

Local

Low

Madi and Kassem. 2018

No

2

14 days

Topical

Low