Skip to main content

Table 3 Characteristics of the included studies

From: The impact of simvastatin intervention on the healing of bone, soft tissue, and TMJ cartilage in dentistry: a systematic review and meta-analysis

Included studies Clear inclusion and exclusion criteria Randomization method Assessment parameters (two or more)/validated measurements Duration of study With/without carrier and route Risk of bias
Vaziri et al. 2007 No 2 4 weeks No carrier/injection Low
Killeen et al. 2012 No 1 48 days Systemic/local injection Low
Kilic et al. 2008 No 2 14 days Systemic/local Low
Rutledge et al. 2011 No 1 60 days Local injections Low
Ozec et al. 2007 No 2 14 days Systemic Low
Sherif et al. 2016 No 1 4 weeks Topical Low
Wu Z et al. 2008 No 2 12 weeks Local Low
Anbinder et al. 2007 Yes 1 35 days Oral Low
George MD et al. 2013 No 1 30 days Injections/carrier Low
Holwegner et al. 2015 No 2 28 days Injections/carrier Low
Gouda et al. 2017 No 2 9 months Local Low
Ranjan et al. 2017 No 2 9 months Local Low
Kinra et al. 2010 No 2 24 weeks Local Low
Chauhan et al. 2015 No 2 3 months Local Low
Pradeep et al. 2012 No 2 6 months Local Low
Madi and Kassem. 2018 No 2 14 days Topical Low