Table 1 OHAT risk of bias assessment
Study | ||||||
|---|---|---|---|---|---|---|
de Oliveira et al. [12] | Pasquali et al. [7] | Payer et al. [2] | Sauerbier et al. [11] | Sauerbier et al. [14] | Wildburger et al. [15] | |
Selection bias | ||||||
Was administered dose or exposure level adequately randomized? | ++ | ++ | ++ | −− | ++ | ++ |
Was allocation to study groups adequately concealed? | NR | NR | NR | −− | + | NR |
Performance bias | ||||||
Were the research personnel and human subjects blinded to the study group during the study? | −− | −− | −− | −− | + | −− |
Detection bias | ||||||
Can we be confident in the exposure characterization? | − | − | − | − | − | − |
Can we be confident in the outcome assessment? | ++ | ++ | ++ | ++ | ++ | ++ |
Attrition bias | ||||||
Were outcome data complete without attrition or exclusion from analysis? | ++ | ++ | + | ++ | − | − |
Reporting bias | ||||||
Were all measured outcomes reported? | ++ | ++ | ++ | ++ | − | − |