Fig. 8From: Direct activation of platelets by addition of CaCl2 leads coagulation of platelet-rich plasmaMechanisms of Ca2+-induced fibrin clot formation in citrated plasma. As a major mechanism, Ca2+ activates the coagulation pathway in cooperation with a glass surface and thus subsequently activates platelets through production of thrombin and fibrin. As an additional mechanism, Ca2+ directly stimulates platelets to promote coagulationBack to article page