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Table 3 Assessment of risk of bias using SYRCLE’s tool

From: Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies

Risk of bias

Study

Maïmoun et al. 2010 [29]

Li et al. 2010 [32]

Li et al. 2012 [33]

Linderbäck et al. 2012 [30]

Chen et al. 2013 [31]

Selection

 Sequence generation

L

L

U

L

L

 Baseline characteristics

L

L

L

L

L

 Allocation concealment

U

L

U

U

U

Performance

 Random housing

U

U

U

U

U

Blinding

U

L

U

L

U

Detection

 Random outcome assessment

U

U

U

U

U

 Blinding

U

U

L

U

U

Attrition

 Incomplete outcome data

U

U

U

U

U

Reporting

 Selective outcome reporting

L

L

L

L

L

Other sources of bias

H

H

H

H

H

  1. L low risk of bias, H high risk of bias, U unclear