Table 1 Patient selection criteria

Inclusion

Male or female

At least 18 years old

Healthy enough to undergo routine implant surgery and subsequent dental treatment

Partially edentulous requiring single dental implants in the maxilla

Adequate volume of native or grafted bone to accommodate dental implants at least 8 mm long

No active infections

Physically, emotionally, and financially able to undergo planned implant procedures

Adequate compliance to meet study requirements and necessary appointments

Exclusion

Medical need for antibiotic premedication for infective endocarditis, artificial joints, or any other medication

Uncontrolled hypertension

Uncontrolled diabetes

Serological human immunodeficiency virus (HIV) positive

History of significant heart, stomach, liver, kidney, blood, immune system, or other organ impairment or systemic disease that would prevent undergoing the proposed treatment

Smoke cigarettes or other tobacco products

Use of investigational drugs during the previous month

Unresolved dental conditions likely to require exiting the study for treatment, such as deep cavities, abscesses, or moderate to severe periodontal disease

History of radiation therapy to the head and neck

Unwilling or inability to sign the informed consent form

Failure to demonstrate willingness to return for a required number of visits

Need immediate dental implant placement following tooth extraction