A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps

International Journal of Implant Dentistry

Table 4 Mean crestal bone level changes, in early loading and conventional loading arms (PPS), 6 months after implant placement

Treatment arm	Summary statistics	Baseline	6 months	Change from baseline to 6 months	12 months	Change from baseline to 12 months
Early loading-arm (N = 38)	No. of patients	38	38	38	38	38
	Mean (SD)	1.342 (0.600)	1.903 (0.603)	0.561^a (0.576)	2.102 (0.483)	0.760^b (0.603)
	Maximum	2.73	2.96	2.21	3.47	2.15
	Third quartile	1.73	2.22	0.88	2.34	1.14
	Median	1.25	2.015	0.55	2.05	0.80
	First quartile	0.98	1.52	0.17	1.77	0.37
	Minimum	0.29	0.48	−0.51	1.24	−0.39
Conventional loading arm (N = 37)	No. of patients	37	37	37	36	36
	Mean (SD)	1.355 (0.724)	1.868 (0.521)	0.513^b (0.617)	2.099 (0.558)	0.734^b (0.77)
	Maximum	3.01	3.81	1.82	3.74	2.54
	Third quartile	1.85	2.07	0.94	2.45	1.185
	Median	1.43	1.83	0.49	2.02	0.61
	First quartile	0.76	1.58	0.07	1.735	0.14
	Minimum	0.27	0.83	−0.71	1.04	−0.66

^aInter-arm difference (6 months): difference in mean 95 % confidence interval 0.048 (−0.227–0.322)
^bInter-arm difference (6 months): difference in mean 95 % confidence interval 0.026 (−0.293–0.346)