In vitro immunological and biological evaluations of the angiogenic potential of platelet-rich fibrin preparations: a standardized comparison with PRP preparations

International Journal of Implant Dentistry

Table 1 Comparison of sample volumes and preparation volumes

	Platelet-poor plasma (PPP)	PPP clot	Platelet-rich plasma (PRP)	PRP clot	Platelet-rich fibrin exudate (PRFexu)	Platelet-rich fibrin extract (PRFext)	Platelet-rich fibrin (PRF) membrane
Starting blood sample volume (mL)	10^a	10^a	10^a	10^a	10	10	10
Resulting sample volume (mL) (vs. starting volume)	2.5 (1:4)		1 (1:10)		1 (1:10)	1 (1:10)	1^b (1:10)
Relative condensation (fold)	1		2.5		2.5	2.5
Volume needed to mold a clot (mL) (vs. resulting sample volume)		0.25 (1:10)		0.2 (1:5)
Number of 5 × 5 × 1-mm membrane		10^c		5^c			5–7^d
Relative condensation (fold)		1		2			1.4–2.0

^aThis sample volume does not include the volume of acid citrate dextrose solution (ACD; 1.5 mL)
^b(Acquired sample volume) = (blood sample volume) − (RBC fraction) − (serum volume)
^cEstimated number of membranes
^dAcquired number of membranes