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Table 10 Included studies—surgical treatment of peri-implantitis: adjunctive resective therapy

From: Efficacy of alternative or adjunctive measures to conventional treatment of peri-implant mucositis and peri-implantitis: a systematic review and meta-analysis

Publication Design Population Case definition Period Test Control Mean (SD) outcome
Romeo et al. [42, 57] RCT, parallel 17 patients Suppuration or sulcus bleeding, PD >4 mm horizontal peri-implant translucency 36 months systemic antibiotic medication (Amoxicillin for 8 days) Full mouth disinfection/mechanical debridement + resective therapy (apical re-positioned flap + bone re-contouring) + decontamination using metronidazole + tetracycline hydrochloride (3 min) + implantoplasty using diamond and arkansas burs/silicone polishers Full mouth disinfection/mechanical debridement + resective therapy (apical re-positioned flap + bone re-contouring) + decontamination using metronidazole + tetracycline hydrochloride (3 min) Test
   22 implants rough surfaces      BOP: 2.83 (0.47) (BL) to 0.5 (0.69) (24 monthsa, implant level)
PD: 5.79 (1.69) (BL) to 3.58 (1.06) mm (24 monthsa, implant level)
        MBL: 0.0–0.01 mm (36 months, implant level)
        Control
        BOP: 2.86 (0.35) (BL) to 2.33 (0.74) (24 monthsa, implant level)
        PD: 6.52 (1.62) (BL) to 5.5 (1.47) mm (24 monthsa, implant level)
        MBL: 1.44–1.54 mm (36 months, implant level)
  1. BL baseline, BOP bleeding on probing, MBL marginal bone loss, PD probing pocket depth, RCT randomized controlled clinical study
  2. aAll patients of the control group were discontinued from the study due to persistent clinical signs of inflammation